Designed for comfort and durability Made of latex-free silicone Can be sterilized by boiling or autoclaving (up to 134˚C) Universal 22mm or 15mm diameter fits all international size ventilation devices. Directions 1. Remove mask from bag 2. Connect mask to the Space Chamber 3. Be sure connection is secure. 4. Place mask firmly over the face, making sure nose and mouth are well covered for an effective seal to optimize delivery of medication.